Browse radioulnar synostosis studies by topic, search their titles and plain-language summaries, and open the original publication.
138articles
10research topics
31 of 138 articles
Journal of the American Academy of Orthopaedic Surgeons
Post-traumatic RUS is a rare complication of forearm / elbow fractures. Early surgery 6-12 months after the initial injury can be helpful if the fused bone is completely taken out.
Read full article (opens in a new tab)Journal of Pediatric Orthopaedics B
Surgery can improve quality of life for children with CRUS by correcting severe fixed pronation, but all methods carry complication risks related to the hardware used to secure rotational osteotomies.
Read full article (opens in a new tab)Orthopaedics & Traumatology: Surgery & Research
Adult post-traumatic RUS is a rare complication of forearm fractures that completely blocks forearm rotation. Risk factors include fractures of both bones at the same level or extensive soft-tissue damage, and delayed or repeated surgery / single surgery for both bones. While there is no clear consensus on the treatment approach, individual planning and intensive rehab is important.
Read full article (opens in a new tab)Journal of Shoulder and Elbow Surgery
This study looked at adults who developed this problem in the forearm after an injury and then had surgery with one surgeon. Most people had the abnormal bone bridge removed (sometimes with extra procedures) and their arm function scores improved a lot after surgery. Surgery usually worked well, but it could still fail or have hardware problems, so planning each operation carefully was important.
Read full article (opens in a new tab)Skeletal Radiology
Imaging from multiple children shows a wide range of ways proximal radioulnar fusion can develop over time. Several distinct patterns on X‑ray and MRI form a continuous spectrum from mild to severe bony changes. Recognizing these patterns can improve early diagnosis and help match treatment to each child’s specific anatomy.
Read full article (opens in a new tab)mdpi.com
The article explains how this condition develops before birth, how often it appears in families, and how it is usually diagnosed with exam and imaging. Several types and severities are described based on X‑ray features and the position of the radial head, but these patterns do not clearly predict function. Treatment options are compared, noting that many children can be managed without surgery, while operations such as rotational osteotomy are reserved for severe cases and carry a real risk of complications.
Read full article (opens in a new tab)tandfonline.com
Recommended management for posttraumatic RUS includes optimizing the original fracture surgery to avoid bone debris between the bones, then another surgery to resection the bridge once the bone has matured, usually around 6-12 months. Other treatments like NSAIDs or low‑dose radiation and early, intensive rehab are reserved for higher‑risk cases.
Read full article (opens in a new tab)sciencedirect.com
Preferred treatment of posttraumatic RUS is surgical excision of the bony bridge once fractures have healed or the synostosis looks stable on X‑ray, sometimes with a tissue layer placed between the bones. Various interposition materials and rehabilitation plans are reported, but no single option clearly works best in all patients.
Read full article (opens in a new tab)pmc.ncbi.nlm.nih.gov
A 14‑year‑old boy with bilateral CRUS also had osteoporosis, repeat low‑energy fractures of the forearm, and a non‑healed ulna fracture. Treatment focused on re‑fixing the ulna with bone grafting plus a structured physiotherapy program, without trying to separate the synostosis. After one year, the fracture was almost healed, forearm motion and daily‑activity scores improved on both sides, and the report concludes that firm fixation, bone grafting, and physiotherapy can be better choices than synostosis surgery for many CRUS patients with osteoporosis.
Read full article (opens in a new tab)pmc.ncbi.nlm.nih.gov
Seven families with RUS and blood problems were studied, totaling nine affected people with issues ranging from a single low blood cell line to full bone marrow failure. Three different germline changes in the MECOM gene (two new) were found in five of these families, while two families had no detectable changes in MECOM or HOXA11. The cases show that the same MECOM variant can cause very different severities and ages of onset, and that RUS with blood problems is often a broad bone marrow failure syndrome rather than just low platelets.
Read full article (opens in a new tab)tandfonline.com
Eleven adults with CRUS described how fixed forearm position limits everyday tasks, but also how they adapt and view it as “their normal” over time. Many reported knowing more about CRUS than their providers and often had to advocate for themselves because medical professionals lacked knowledge. The study highlights the need for individualized, client‑centered rehab, better communication, and stronger advocacy so people with CRUS can access appropriate support and accommodations.
Read full article (opens in a new tab)sciencedirect.com
The article reviews both congenital and acquired forms of radioulnar synostosis, with emphasis on how they limit forearm rotation and daily function. Key sections cover typical anatomy changes, imaging findings, and indications for surgery versus conservative management in congenital cases. Treatment options, including derotational osteotomy for CRUS and resection with interposition for post‑traumatic cases, are summarized with their main benefits and risks.
Read full article (opens in a new tab)mdpi.com
Children with CRUS in several hospitals were checked to see how they did with and without surgery. Surgery that rotated the forearm bones closer to neutral improved arm position by about 60° and helped most children use their arms better, with fewer than 1 in 10 having problems. Some children with mild deformity did well without surgery, but those with very strong fixed pronation gained more independence in daily tasks after derotational osteotomy.
Read full article (opens in a new tab)onlinelibrary.wiley.com
A large family with CRUS across three generations was described, with several members in each generation affected. Pedigree analysis supported autosomal dominant inheritance with variable expression, meaning some relatives had more severe deformity than others. The report highlights that CRUS can run strongly in families and that genetic counseling may be useful for affected kindreds.
Read full article (opens in a new tab)sciencedirect.com
The article summarizes how to time surgery (usually 6-12 months after injury when extra bone has matured) and explains which open surgical approach to choose based on where the bridge is and how far it extends. After excision, covering the raw bone with interposition tissue and starting early motion are recommended to lower the risk of the bridge growing back.
Read full article (opens in a new tab)sciencedirect.com
A baby with unilateral CRUS was not clearly diagnosed before birth, even though careful review of pregnancy ultrasounds later showed subtle elbow and forearm changes. The report explains which prenatal ultrasound and postnatal X‑ray signs can suggest CRUS and how easily the diagnosis can be missed. The authors recommend closer follow‑up and better imaging protocols when a fetus shows persistent abnormal forearm position, so families can receive earlier counseling and planning.
Read full article (opens in a new tab)frontiersin.org
Ten children with proximal CRUS (12 forearms) had derotational osteotomies of the distal radius and proximal ulna fixed with plates, moving the forearm from an average of about 57° pronation to around neutral, with roughly 53° of correction. All osteotomies healed, Failla function scores improved from mostly fair/poor to mostly good/excellent, and no nerve, blood‑flow, or infection problems were reported. The paper also summarizes other osteotomy methods and supports plate‑fixed two‑bone derotation between ages 3-9 as a safe way to place the forearm in a more useful position.
Read full article (opens in a new tab)frontiersin.org
In 329 children with CRUS, most had Type III changes on X‑ray, and this group almost always showed severe fixed pronation over 60°. The newer CMPOS system matched X‑ray types to clinical severity: Type I mainly had neutral or mild pronation, Type II moderate pronation, and Type III severe pronation. The study suggests that children with Type III in either system are more likely to need early intervention, while many with milder types can be managed with observation or physiotherapy.
Read full article (opens in a new tab)onlinelibrary.wiley.com
People with SMAD6 gene changes often had RUS, sometimes with other bone differences in the skull or spine. SMAD6 loss‑of‑function variants were much more common in people with RUS than in healthy controls, showing this gene is a major cause of the condition. Many affected people had stable bone changes without life‑threatening illness, so care usually focused on watching growth and function rather than routine surgery.
Read full article (opens in a new tab)sciencedirect.com
Adults who had distal biceps tendon repair were checked to see how often painful radioulnar synostosis developed. Patients who took indomethacin after surgery had about a 1% synostosis rate, compared with about 38% in those who did not take it. No clear side effects like stomach bleeding or tendon re‑tear were linked to indomethacin in this group.
Read full article (opens in a new tab)nature.com
Children with congenital proximal radioulnar synostosis had MRI and X‑ray scans to measure the size of the supinator muscle and the shape of the bones. A new three‑type system was created that groups cases by whether the bridge is fibrous or bony and how well the supinator is developed. Supinator muscle was present in every case, and its size clearly matched how severe the bony deformity looked on imaging.
Read full article (opens in a new tab)pmc.ncbi.nlm.nih.gov
Twenty patients with unilateral proximal CRUS and no surgery had wrist motion measured using a 3‑D motion analysis system. In patients older than 10 years, the affected side showed greater wrist rotation, especially more pronation, than the normal side, showing a clear compensatory hypermobility pattern. The 3‑D method closely matched goniometer readings and showed excellent reliability for measuring wrist rotation.
Read full article (opens in a new tab)saspublishers.com
A 55‑year‑old woman developed radioulnar synostosis after an open both‑bone forearm fracture treated with intramedullary wires, where leftover fragments filled the interosseous space. Nine months later, the forearm was fixed with loss of pronation, and imaging showed a solid bone bridge between radius and ulna. Surgical excision of the bridge without interposition tissue, plus early physiotherapy, restored good pronation-supination by 12 months with no recurrence.
Read full article (opens in a new tab)academic.oup.com
One adult soldier with radioulnar synostosis is described, with the condition causing limits in forearm rotation but not preventing work as a generator mechanic. Functional, cosmetic, and cultural challenges from the condition are outlined along with how this individual adapted to military duties. Published treatment options in the literature are briefly reviewed, emphasizing that many people can function well without surgery depending on job demands and severity of deformity.
Read full article (opens in a new tab)journals.lww.com
A new X‑ray angle called the radial pronation angle is described to measure how much the radius is turned in children with radioulnar synostosis. Higher angles match more severe turning of the forearm and worse ability to rotate the arm. This angle provides doctors with a simple, repeatable way to grade deformity and help plan if surgery is needed.
Read full article (opens in a new tab)academic.oup.com
A 7-year-old boy developed distal radioulnar synostosis after a high-energy road traffic accident and initial open reduction and fixation of both forearm bones. One year later, synostosis resection with interposition of autologous fat restored full forearm rotation, with no recurrence at 16-month follow-up. A brief review of recent pediatric cases shows that early surgical resection with or without biological interposition with early rehabilitation usually leads to good motion and low recurrence.
Read full article (opens in a new tab)sciencedirect.com
A de novo missense change in the ZMAT2 gene was found in a 5-year-old boy with radioulnar synostosis using whole-exome sequencing. In zebrafish, lowering zmat2 levels caused fin and body patterning defects consistent with reduced bone morphogenetic protein signaling, which could be rescued by normal but not mutant zmat2. These findings show that ZMAT2 helps control bone development through the BMP pathway and that damaging mutations in this gene can contribute to radioulnar synostosis.
Read full article (opens in a new tab)dl.acm.org
An automated 3D measurement method is introduced to calculate several deformity angles and rotation parameters in congenital radioulnar synostosis using CT-based models. The system quantifies factors like radial and ulnar angulation and internal rotation, then summarizes deformity severity into indices that match clinical patterns. These automated measurements are designed to support diagnosis and to guide osteotomy planning by giving surgeons objective numbers for the deformities.
Read full article (opens in a new tab)boneandjoint.org.uk
The piece outlines different ways to manage post-traumatic radioulnar synostosis, including timing of surgery, how much bone to remove, and whether to add soft-tissue or flap interposition between the radius and ulna. Advantages and drawbacks of these options are compared, with emphasis on preventing recurrence and restoring useful forearm rotation. A practical treatment strategy is proposed to help surgeons choose the best approach based on synostosis location, patient needs, and risk factors.
Read full article (opens in a new tab)journal.rniito.org
Many different osteotomy techniques for kids with radioulnar synostosis are summarized, focusing on what age to operate, how much to rotate the forearm, and where to cut the bones. Most children had surgery around age 5, bones usually healed in about 6–8 weeks, and target positions were near neutral or slight pronation/supination depending on side and whether one or both arms were involved. Cutting directly through the synostosis carried a much higher risk of nerve and blood vessel problems than cutting both forearm bones away from the fusion area.
Read full article (opens in a new tab)sciencedirect.com
Radioulnar synostosis is described together with blood problems like low platelets and bone marrow failure, and with specific gene changes. Known links include variants in the MECOM gene and named syndromes where arm bone changes occur with serious blood count problems. The article groups these medical and genetic findings to show how arm bone fusion and blood diseases are connected in several inherited conditions.
Read full article (opens in a new tab)These summaries are a starting point, not medical advice or a substitute for reading each paper. Study methods, quality, and conclusions vary. Follow the source link for the full publication and discuss personal medical questions with a qualified clinician.
